Infusion Therapy for Gout

Posted by Encore Infusion Site Administrator


Gout is a form of arthritis caused by excess uric acid in the bloodstream. It manifests as joint pain accompanied by swelling, redness and limited range of motion. The pain usually comes on suddenly and can cause a sensation of warmth at the affected area. While there are more than 100 types of arthritis—each with varying causes, risk factors and symptoms—gout is among the most common.

Gout typically occurs in the feet and most often at the base of the big toe. Other less common areas include the knee, hand, wrist and elbow. It’s more likely to affect men, post-menopausal women, diabetics, people with poor kidney function and those with other underlying health conditions.

Gout has no cure, but can be managed with medication. Often patients are prescribed oral medications including NSAIDs, colchicine, allopurinol and corticosteroids. Some patients experience periods of remission of a year or longer, in which case oral medications for the occasional flare-up can be sufficient. However, gout pain can also occur more often, in which case infusion therapy can help.

Pegloticase (trade name Krystexxa) is an IV medication for the treatment of severe and chronic gout. It is a treatment for those whose other treatments are not tolerated or not otherwise working. In clinical trials, Krystexxa was shown to lower levels of uric acid and reduce deposits of uric acid crystals in joints and soft tissue. Typically, Krystexxa is administered every two weeks over a six-month period, and takes about two hours per infusion.

If you are struggling with frequent flare-ups from gout and oral medications are not controlling your condition, you might be a candidate for Krystexxa. Please contact your physician to inquire about this infused medication or contact Encore Infusion and we’ll guide you through the process of making a physician request for this treatment.